Since 2013, the research group has tested more than 1,000 ready-made drugs on nematode worms, human cells in a dish and mice.
Two were shown to prevent both a form of dementia and prion disease by stopping brain cells dying.
Prof Mallucci told the BBC News website: "Both were very highly protective and prevented memory deficits, paralysis and dysfunction of brain cells."
The best known drug of the pair is trazodone, which is already taken by patients with depression.
http://www.bbc.com/news/health-39641123
trazodoneが一般名、レスリンが商品名な